Humans aren't the only things that call this charming Southern city home.

Bed Bugs
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Bed bugs are an unfortunate reality of life in most major cities. But not every urban area experiences the same struggle with these tiny, bloodsucking pests—one city in particular has consistently played host to the most bedbug infestations in the country.

According to a recent report from Orkin, for the third year in a row, Baltimore ranks number one on the pest control company's list of America's "Top 50 Bed Bug Cities."

The only other Southern city to make the unlucky list is Washington D.C., which took the number two spot behind Charm City.

Bed bugs are nocturnal insects that take up residence in walls and furniture, emerging at night to dine on the blood of sleeping humans. To make matters even more horrifying, bed bug infestations are costly, time-consuming and traumatic to remedy.

"Bed bugs are the No. 1 urban pest in many cities today," Chelle Hartzer, an Orkin entomologist, said in a statement. "They are master hitchhikers, so no one is immune. Sanitation has nothing to do with prevention: from public transit to five-star resorts, bed bugs have been and can be found everywhere humans are."

WATCH: How To Check For Bed Bugs In A Hotel

Orkin recommends inspecting your home for signs of bed bugs regularly. Check the places where they hide during the day, including mattress tags and seams, and behind baseboards, headboards, electrical outlets and picture frames. Contact a pest management professional immediately if you suspect a bed bug infestation.

For Orkin's complete "Top 50 Bed Bug Cities" list, visit