Glorious stretches of open road await in the South. You can drive well-traveled miles on the Blue Ridge Parkway and Skyline Drive. Or take a tropical trek down U.S. 1 to Key West. For an undiscovered jaunt through the peaks of Tennessee and North Carolina, hit the Cherohala Skyway. But for sheer nostalgia, remember the song and get some kicks. Follow Route 66, where it rolls across the open miles of Oklahoma.